From McGill


  • Lokha R. Alagar BoopathyEmma BeadleAlan XiaoAitana Garcia-Bueno RicoCelia AleckiIrene Garcia de-AndresMaria Vera. The ribosome quality control factors Asc1 and Hel2 regulate the expression of HSP70 during heat shock and recovery.
  • Wefers, Z.* & Alecki, C.*, Huang R., Jacob-Tomas, S., and Vera, M. Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment. Cells. 11(12):1877. PMID:35741005. (*) = Equal contribution to this work.
  • Jacob-Tomas, S.* & Alagar Boopathy, L.R.*, and Vera, M. Using single-molecule fluorescence microscopy to uncover neuronal vulnerability to protein damage. Invited contribution to Methods in Molecular Biology: Neuronal Cell Death: Methods and Protocols. 2022;2515:237-254  (*) = Equal contribution to this work. PMID: 35776356.
  • Alagar Boopathy, L.R.* & Jacob-Tomas, S.*, Alecki, C., and Vera, M. Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges. Invited contribution to J Biol Chem. 2022 Mar 3;101796. PMID: 35248532. (*) = Equal contribution to this work.
  • Alecki, C and Vera, M. Role of nuclear non-canonical nucleic acid structures in organismal development and adaptation to stress conditions. Front Genet. 2022 Feb 23;13:823241. PMID: 35281835.


  • Das, S., Vera, M., Gandin, V., Singer, R.H.*, and Tutucci, E*.  Intracellular mRNA transport and localized translation. Nature Review in Molecular Cell Biology. Jul;22(7):483-504. PMID: 33837370.


  • Sato. H* & Das. S*, Singer. RH and Vera, M.  Imaging of DNA and RNA in Living Eukaryotic Cells to Reveal Spatiotemporal Dynamics of Gene Expression. Annual Review of Biochemistry, Vol (89). PMID:32176523.

First-author publications (Ph.D. and Postdoc)

  • Vera, M., Tutucci, E., and Singer, R.H. (2019). The new MS2 system as a tool to visualize single mRNAs in mammalian cells. Methods in Molecular Biology. 2038:3-20. PMID: 31407274.
  • Tutucci, E.*, & Vera, M.*, Biswas, J., Garcia, J., Parker, R., and Singer, R.H. (2018). An improved MS2 system for accurate reporting of the mRNA life cycle. Nature Methods, 15(1): 81-89. (*) = Equal contribution to this work. F1000 recommended.
  • Vera, M., Biswas, J., Senecal, A., Singer, R.H., and Park H.Y. (2016). Single-cell and single-molecule analysis of gene expression regulation. Annual Rev. Genet., 50: 267-291. PMCID: PMC5149423.
  • Hocine, S.* & Vera, M.*, Zenklusen, D., and Singer R.H. (2015). Promoter-Autonomous Functioning in a Controlled Environment using Single Molecule FISH. Sci Rep., 5: 9934. PMCID: PMC4446897. (*) = Equal contribution to this work.
  • Vera, M., Pani, B., Griffiths, L.A., Muchardt, C., Abbott, C.M., Singer, R.H., and Nudler, E. (2014). eEF1A1 couples transcription to translation during heat shock. Elife., 3: e03164. PMCID: PMC4164936.
  • Vera, M. and Singer, R.H. (2014). Gene Regulation: the HSP70 gene jumps when shocked. Current Biol., 24(10): R396-8. PMCID: PMC4156153.
  • Vera, M., Sobrevals, L., Zaratiegui, M., Martinez, L., Palencia, B., Rodríguez, C.M., Prieto, J., and Fortes, P. (2007). Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis. Gene Ther., 14(3): 203-10. PMID: 17024107.
  • Vera, M., Razquin, N., Prieto, J., Melero, I., Fortes, P., and González-Aseguinolaza, G. (2005). Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells. l Ther., 12(5): 950-9. PubMed PMID: 15921960.
  • Vera, M., Prieto, J., Strayer, D.S., and Fortes, P. (2004). Factors influencing the production of recombinant SV40 vectors. Ther., 10(4): 780-91. PMID: 15451462.
  • Vera, M. and Fortes, P. (2004). Simian virus-40 as a gene therapy vector. DNA Cell Biol., 23(5): 271-82. Review. PMID: 15169607.


  • Tutucci, E., Vera, M., and Singer, R.H. Single mRNA detection in living S. cerevisiae using a re-engineered MS2 system. Nature Protocols. Oct;13(10):2268-2296. PMID: 30218101.
  • Doig, J., Griffiths, L.A., Peberdy, D., Dharmasaroja, P., Vera, M., Davies, F.J., Newbery, H.J., Brownstein, and D., Abbott, C.M. (2013). In vivo characterization of the role of tissue-specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy. FEBS J., 280(24): 6528-40. PMCID: PMC4163635.
  • Urtasun, R., Cubero, F.J., Vera, M., and Nieto, N. (2009). Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha. Gastroenterology, 136(4): 1410-22, PMID: 19250650.
  • Abad, X., Vera, M., Jung, S.P., Oswald, E., Romero, I., Amin, V., Fortes, P., and Gunderson, S.I. (2008). Requirements for gene silencing mediated by U1 snRNA binding to a target sequence. Nucleic Acids Res., 36(7): 2338-52. PMCID: PMC2367729.
  • Narvaiza, I.*, Aparicio, O.*, Vera, M., Razquin, N., Bortolanza, S., Prieto, J., and Fortes, P. (2006). Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing. Virol., 80(24): 12236-47. PMCID: PMC1676304.
  • Huarte, E., Tirapu, I., Arina, A., Vera, M., Alfaro, C., Murillo, O., Palencia, B., Busto, V., Marín, V., Mazzolini, G., and Melero, I. (2005). Intratumoral administration of dendritic cells: hostile environment and help by gene therapy. Expert Opin. Biol. Ther., 5(1): 7-22. Review. PMID: 15709906.
  • McKee, H.J., T’sao, P.Y., Vera, M., Fortes, P., and Strayer, D.S. (2004). Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15. Vaccines Ther., 2(1): 10. PMCID: PMC517511.
  • Pérez-Caballero, D., González-Rubio, C., Gallardo, M.E., Vera, M., López-Trascasa, M., Rodríguez de Córdoba, S., and Sánchez-Corral, P. (2001). Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome. J. Hum. Genet., 68(2): 478-84. PMCID: PMC1235280.

María Vera Ugalde

McIntyre Medical Sciences Building
3655 promenade Sir-William-Osler
Montreal, Quebec H3G 1Y6